Bedrock Layout Primitives are built using Bedrock Layout CSS. Just simply import the Bedrock Layout CSS into your app and you're ready to go.
Bedrock Layout Primitives are built to allow you to compose them together to create your own custom layouts. Many "complex" layouts can be created by composing Bedrock Layout Primitives.
You can use Bedrock Layout Primitives with any design system. Bedrock Layout's' spacing scheme can be easily overridden to match your design system.